Waymire completed a Bachelor of Fine Arts in Theater at SMU, later earning a Master's degree in Fine Arts from the University of California, San Diego in 1993.
After graduating from college, Waymire moved to New York City. She began her television career in the role of "Emily" on the soap opera One Life to Live in 1994.
In addition to film and television work, Waymire was active in regional theater throughout the United States. She played the lead in A.R. Gurney's play Sylvia at San Diego's Old Globe Theatre in 1996. She appeared in a revival of the Noël Coward play Present Laughter at the Pasadena Playhouse in 1998, as well as many other stage productions across the country. At the time of her death, Waymire was starring as "Anne" in the stage adaptation of Kate Crackernuts, at the 24th Street Theatre in Los Angeles.
In 1997, Waymire moved to Los Angeles. She continued her career in a number of primetime television shows, including The Practice, Judging Amy, The X-Files, Wolf Lake, CSI: Crime Scene Investigation, NYPD Blue, and Yes Dear.
On December 8, 2003, a public memorial was held at the Ralph Freud Playhouse, Macgowan Hall at UCLA.
