Younger sister of Kourtney and Kim Kardashian who gained fame on the reality television program Keeping Up with the Kardashians and co-hosted The X Factor with Mario Lopez.
She dropped out of high school, but continued her education as a home school student.
She appeared on The Celebrity Apprentice in 2009, and worked as a model and a boutique owner. She also starred in the spin-off reality television series Kourtney and Khloé Take Miami and Khloé & Lamar.
She married NBA star Lamar Odom in September 2009 after meeting him at one of Metta World Peace's parties. During a hiatus with Odom, she dated Rapper French Montana and NBA star James Harden. In 2016, she began a relationship with Tristan Thompson and the pair welcomed a baby girl on April 12, 2018.
Her half-sisters are Kylie and Kendall Jenner.