Created a charitable foundation with her husband Bill Gates.
She earned a computer science and economics degree and later an MBA, both from Duke University.
She was the project manager for Microsoft Bob, Microsoft Encarta, and Expedia.
She had her first child, Phoebe in September 2002. Her mother was a homemaker and her father was an engineer.
She and her husband were deemed Persons of the Year with Bono by Time magazine in 2005.