"You never say never. but I am very, very comfortable in the position I’m in with Lucha Underground. I love their schedule, I love their style, I love what they have to offer. I don’t think there will ever be another company that has what Lucha Underground has. It’s very unique, exciting, and fresh—this is really something new".
Gutierrez made his debut in Mexico on April 30, 1989, when he was 14 years old. He was trained by his uncle Rey Misterio Sr. and wrestled early on in Mexico where he learned the Lucha Libre high flying style that has been his trademark. He had ring names such as "La Lagartija Verde (The Green Lizard)" and "Colibrí (Humming bird)" before his uncle gave him the name of Rey Misterio Jr. In 1991, Mysterio was awarded "Most Improved Wrestler" in Mexico while wrestling as Colibrí.
Widely regarded as the greatest cruiserweight Wrestler of all time, Mysterio is known for his high-flying Lucha libre wrestling style, which is credited with having helped kick-start the emergence of cruiserweight wrestling in the United States in the mid-1990s. Championships held by Mysterio over the course of his career include WWE's World Heavyweight Championship, the WWE Championship, WCW/WWE Cruiserweight Championship, WCW World Tag Team Championship, WCW Cruiserweight Tag Team Championship, WWC World Junior Heavyweight Championship, WWE Tag Team Championship, and WWE Intercontinental Championship. He is also the twenty-first WWE Triple Crown Champion and the winner of the 2006 Royal Rumble match.
Mysterio signed with Paul Heyman's Extreme Championship Wrestling (ECW) in 1995. He debuted in September at Gangstas Paradise, defeating Psicosis, who was also making his ECW debut. A feud between the two began, which included a two out of three falls match and a Mexican Death match. Mysterio also had a series of matches with ECW-newcomer Juventud Guerrera during the first half of 1996.
Mysterio made his World Championship Wrestling (WCW) debut on June 16, 1996, at The Great American Bash, challenging Dean Malenko for the WCW Cruiserweight Championship, which Malenko retained by winning. In July at Bash at the Beach, he defeated longtime rival Psicosis in a number one contender's match to earn another opportunity at the Cruiserweight title. The next night, on the July 8 episode of WCW Monday Nitro, he defeated Malenko to win his first Cruiserweight Championship. He reigned as champion for three months, which included title defenses against the likes of Ultimate Dragon, Malenko, and Super Caló before he lost the title to Malenko at Halloween Havoc. Following his Cruiserweight Championship reign, Mysterio challenged Ultimate Dragon for the J-Crown Championship, but was unsuccessful in his title match at World War 3 in November.
Gutierrez and his wife Angie have two children: one son, Dominic, born 1997 and a daughter, Aalyah, born 2001. He has tattoos of his children's names on his right and left biceps, tattoos dedicated to his wife, Angie, and a tattoo with the initials EG for his best friend and fellow Wrestler, Eddie Guerrero, who died in 2005. He is a devout Roman Catholic, frequently crossing himself before every match and bearing numerous religious tattoos on his body, most notably a cross on his chest attached to rosaries as well as other crosses and allusions to God.
On the January 15, 1998, episode of WCW Thunder, Mysterio defeated Juventud to win his third Cruiserweight Championship, but lost it nine days later to Chris Jericho at Souled Out. After the match, Jericho continued the beating by using a toolbox he found at ringside. This storyline was used to cover Mysterio's need for a knee operation that kept him out of the ring for six months. He made his return at Bash at the Beach, where he defeated Jericho for his fourth Cruiserweight championship. The next night, however, the result was overturned and the belt returned to Jericho due to Dean Malenko interfering. Later that year, Eddie Guerrero formed a Mexican stable known as the Latino World Order (LWO) (a spin off of New World Order) that included nearly every luchador in the promotion. Mysterio continually refused to join and feuded with Guerrero and the LWO members, including winning a match against longtime rival and LWO member Psicosis in a match at Road Wild. He was finally forced to join the group after losing a match to Eddie Guerrero. Mysterio's on-and-off tag team partner Billy Kidman joined him during the feud with LWO, wrestling against the LWO despite Mysterio being a part of the group. His alliance with Kidman was formed after Mysterio helped Kidman defeat Juventud for the Cruiserweight Championship at World War 3. Mysterio went up against Kidman for the title at Starrcade but was unsuccessful winning back the title in a triangle match that also involved Juventud. Kidman once again defeated Mysterio for the title at Souled Out in a fatal four-way match that also included Psicosis and Juventud.
In mid-1999, Mysterio and Konnan joined Master P's No Limit Soldiers, and began feuding with The West Texas Rednecks. At The Great American Bash, they defeated Rednecks members Curt Hennig and Bobby Duncum Jr. in a tag team match. At Bash at the Beach, they defeated the Rednecks in a four-on-four elimination tag team match when Mysterio pinned Hennig. After Master P's departure from WCW, Mysterio formed a stable with Eddie Guerrero and Billy Kidman known as the Filthy Animals, thus turning heel in the process. This was Mysterio's only heel turn in his career. The three Wrestlers soon began a feud with the Dead Pool. The Filthy Animals defeated the Dead Pool in a six-man tag team match at Road Wild and at Fall Brawl. On the August 19 episode of Thunder, Mysterio lost the Cruiserweight Title to Lenny Lane.
Mysterio appeared in the 2000 film Ready To Rumble along with several other Wrestlers.
At the beginning of 2001, the Filthy Animals feuded with Team Canada, to whom they lost in a Penalty Box match at Sin. At SuperBrawl Revenge, Mysterio unsuccessfully challenged Chavo Guerrero Jr. for the Cruiserweight Title. Kidman and Mysterio participated in a Cruiserweight tag team tournament for the newly created WCW Cruiserweight Tag Team Championship and advanced to the final round where they ended up losing to Elix Skipper and Kid Romeo. On the final episode of Nitro on March 26, they defeated Skipper and Romeo in a rematch to win the Cruiserweight Tag Team Titles before WCW was sold to the World Wrestling Federation (WWF).
Mysterio made his WWE debut on the July 25, 2002, episode of SmackDown! as a fan favorite in a match against Chavo Guerrero, which Mysterio won. He eventually began a feud with Kurt Angle, which culminated in a match at SummerSlam that Angle won after forcing Mysterio to submit to the ankle lock. He later formed a tag team with Edge; the two participated in a tournament for the newly created and SmackDown!-exclusive WWE Tag Team Championship. They lost to Kurt Angle and Chris Benoit in the finals of the tournament at No Mercy; the match was voted match of the year by the Wrestling Observer Newsletter. After they failed to win the title, Mysterio and Edge defeated Los Guerreros in a number one contender's match on the October 24 episode of SmackDown! to earn a title shot. Two weeks later on November 7, they defeated Angle and Benoit in a two out of three falls match to win their first Tag Team Championship. They soon lost the tag titles to Los Guerreros in a Triple Threat Elimination match that also involved former champions Angle and Benoit at Survivor Series. Shortly after the loss, Mysterio and Edge disbanded as a tag team.
On the March 6, 2003, episode of SmackDown!, Mysterio defeated Tajiri and Jamie Noble in a Triple Threat match to earn a shot at the WWE Cruiserweight Championship. At WrestleMania XIX, he challenged the champion Matt Hardy for the title, but lost after Shannon Moore interfered. On the May 22 episode of SmackDown!, Mysterio defeated Shannon Moore and Crash Holly in a handicap elimination match to regain the number one contendership for the Cruiserweight title, and he defeated Hardy to win his first Cruiserweight Championship (his first reign in WWE and his first singles championship in the WWE) on the June 5 episode of SmackDown!. Mysterio's reign ended when he lost the title to Tajiri on the September 25 episode of SmackDown!. Three months later, on the January 1, 2004, episode of SmackDown!, Mysterio defeated Tajiri to win his second Cruiserweight Championship. After a successful title defense against Jamie Noble at Royal Rumble, Mysterio lost the title to Chavo Guerrero at No Way Out in February. At WrestleMania XX, Mysterio took part in a Cruiserweight Open for the title, but Chavo retained the title. On the June 17 episode of SmackDown!, he defeated Chavo Classic for a record-setting third Cruiserweight Championship reign. He successfully defended the title against Classic's son Chavo Guerrero at The Great American Bash. While Mysterio was Cruiserweight Champion, Spike Dudley turned heel after plowing Mysterio through a table and joined the other Dudleys before winning the Cruiserweight Title from Mysterio on the July 29 episode of SmackDown!. At Survivor Series, he participated in a fatal four-way match for the Cruiserweight Title involving the champion Spike, Chavo Guerrero, and Billy Kidman. Mysterio lost when Dudley pinned Guerrero to retain.
The match at WrestleMania was part of a storyline in which Guerrero turned on Mysterio and beat him up after abandoning him during a match against MNM for the Tag Team Championship. Then after a no disqualification match against Chavo, Eddie came out and slammed Mysterio on the steel steps, displaying Eddie's increasing frustration with being unable to defeat Mysterio. Guerrero and Mysterio continued to feud, with Guerrero threatening to reveal a secret he and Mysterio shared involving Mysterio's real life son Dominick, unless Mysterio deferred to Guerrero's authority. Guerrero later revealed that, in the storyline, he was Dominick's biological father. The storyline went that Guerrero knew Mysterio was having trouble starting his own family, so Guerrero left Dominick as a baby with Mysterio and his wife Angie to raise. In subsequent weeks, Guerrero threatened to take custody of Dominick, drawing up custody papers and having his Lawyer present them to Mysterio. At SummerSlam, Mysterio defeated Guerrero in a ladder match for the custody of Dominick. Their feud ended when Guerrero gained a victory over Mysterio in a steel cage match. On November 13, 2005, Eddie Guerrero was found dead in his hotel room in Minneapolis, Minnesota. That same day at a WWE "Super Show" where SmackDown! and Raw were both taped, Mysterio gave an emotional speech about Guerrero, and in a show of respect removed his mask (though he put his head down, so no one could see his face). Mysterio went on to defeat Shawn Michaels in an interpromotional match later that night. After the match, Michaels and Mysterio hugged in the ring and Mysterio pointed up to the sky, crying, in memory of Guerrero.
Mysterio is a playable character in numerous video games: WWE SmackDown! Here Comes The Pain, WWE SmackDown! vs. Raw, WWE Day of Reckoning 2, WWE SmackDown vs. Raw 2006, WWE SmackDown vs. Raw 2007, WWE SmackDown vs. Raw 2008, WWE SmackDown vs. Raw 2009, WWE SmackDown vs. Raw 2010, WWE Legends of WrestleMania, WWE SmackDown vs. Raw 2011, WWE All Stars, WWE '12, WWE '13, WWE 2K14, and WWE 2K15.
On March 19, 2007, Sports Illustrated posted on its website an article in its continuing series investigating a steroid and HGH ring used by a number of professional athletes in several Sports. That article mentioned several current and former WWE Wrestlers, including Gutierrez who was alleged to have obtained nandrolone and stanozolol. WWE subsequently stated that the allegations preceded the Talent Wellness program WWE launched in February 2006. On August 27, 2009, WWE announced that Gutierrez would receive a 30-day suspension due to a violation of the wellness program. Days later Gutierrez defended himself in a newspaper interview by explaining the drugs as being on a prescription for his knee and arm. While the Wellness Policy allows for prescribed drugs, Gutierrez further contested he had been on a family holiday and subsequently in Europe promoting SummerSlam, giving him only a day to provide the prescription after being notified. On April 26, 2012, WWE suspended Gutierrez for 60 days due to a second violation of their wellness program.
Mysterio made his return on the June 23, 2008, episode of Raw, as the first Wrestler to be drafted in the 2008 WWE Draft from SmackDown to the Raw brand. Mysterio made his Raw in-ring debut on July 7, pinning Santino Marella after a 619. General Manager Mike Adamle announced that John Cena was injured and that Mysterio would replace him in the Championship Scramble at Unforgiven. The next week, Mysterio made his return to Raw after an extended absence by attacking Kane, turning back numerous claims that Kane had "ended his career". Mysterio then made his in-ring return at Unforgiven, competing in the Raw Championship scramble match. Mysterio put his mask on the line in a singles match at No Mercy, which he won by disqualification after Kane attacked him with a steel chair. He defeated Kane again at Cyber Sunday, this time in a No Holds Barred match, and again at Survivor Series, when the pair were on opposing sides in a five-on-five elimination match. Mysterio participated in the 2009 Royal Rumble match, entering first and spending 49 minutes and 24 seconds in the match, before being eliminated by the Big Show. The following night on Raw, he qualified for the Elimination Chamber match for the World Heavyweight Championship at No Way Out, but was eliminated by Edge when the two were the last men in the Chamber match.
Later, John "Bradshaw" Layfield (JBL) accepted Mysterio's challenge for Layfield's Intercontinental Championship at WrestleMania XXV, which Mysterio won in 21 seconds. His win made Mysterio the twenty-first Triple Crown Champion in WWE history. Mysterio was drafted back to SmackDown! during the 2009 WWE Draft on the April 13 episode of Raw, in the process making the Intercontinental Title exclusive to SmackDown for the first time since mid-2002. He then began an extended feud with Chris Jericho, successfully defending his title at Judgment Day. At Extreme Rules, Jericho managed to unmask Mysterio and pin him for the Intercontinental Championship; while Mysterio managed to cover his face after being unmasked, Jericho took the opportunity to roll him up and win the title. As a result, Mysterio and Jericho were booked in a Title vs. Mask match at The Bash, Mysterio emerged from the acclaimed match victorious after tricking Jericho with a second mask. He then moved into a feud with Dolph Ziggler, defeating him at both Night of Champions and SummerSlam. On August 2, WWE announced that Mysterio would be suspended for 30 days, effective September 2, for violating the company's Wellness Policy. In an interview with Mexican newspaper Record, Mysterio stated that he was suspended for a drug he was using for his knee and arm. Mysterio stated that he had a prescription for the drug, but was unable to produce it in time to prevent his suspension due to being on vacation and doing a promotional tour. On the September 4 episode of SmackDown (taped on September 1), Mysterio lost the Intercontinental Championship to John Morrison.
Mysterio returned from his suspension at Hell in a Cell, teaming with former tag team partner Batista to face Jeri-Show (Chris Jericho and Big Show) for the Unified Tag Team Championships. They failed to win the titles, as Mysterio was KO punched and pinned by Big Show. At Bragging Rights, Mysterio was unsuccessful in winning the World Heavyweight Championship in a Fatal Four-Way match involving Batista, CM Punk, and then-champion The Undertaker. During the match, Mysterio broke up Batista's pin on Undertaker possibly costing him the match and the title. After the match, Batista turned heel and attacked him. Mysterio faced Batista at Survivor Series, where he lost by Referee stoppage after Batista performed three Batista Bombs on him. Mysterio was defeated by Batista again in a street fight on December 11 episode of SmackDown. A few weeks later Mysterio defeated Batista and was named the number one contender for the World Heavyweight Championship, but his title match against The Undertaker ended in a no contest after Batista interfered. On January 1, 2010, Mysterio participated in a Beat the Clock Tournament for a World Heavyweight Championship at the Royal Rumble. In the tournament, he defeated his former rival Chris Jericho in the quickest time, and prevented Batista from beating it by interfering in his match. This led to a number one contender's match between the duo the following week, which also ended in a no contest following interference from the Undertaker. The following week in a re-match, Mysterio defeated Batista in a Steel Cage match, but failed to win the championship at the Royal Rumble.
In the 2011 WWE Draft, Mysterio was drafted back to Raw. On the May 9 episode of Raw, Mysterio lost a triple threat match to determine the number one contender for the WWE Championship. Following the match, Mysterio was attacked by R-Truth, which led to a match between the two at Over the Limit, which R-Truth won. From May, Rey Mysterio started feuding with CM Punk, with the pair exchanging victories on consecutive episodes of Raw. The feud culminated in a singles match on June 19 at WWE Capitol Punishment, where Punk emerged victorious. On July 17 at Money in the Bank, Mysterio failed to capture the Raw Money in the Bank briefcase, as the match was won by old rival Alberto Del Rio. The following night on Raw, Mysterio took part in a tournament for the vacant WWE Championship and advanced to the finals. On July 25, Mysterio defeated Miz in the final to win his first WWE Championship, but he lost the title to John Cena later that night. On August 15, Mysterio received a rematch for the WWE Championship against new champion Alberto Del Rio, but lost. Mysterio suffered an injury in late August 2011, and a storyline was put in place to write Mysterio off television, by blaming Alberto Del Rio. Mysterio returned at the Slammy Awards to present the Superstar of the Year Award to CM Punk.
On April 26, 2012, WWE reported that Mysterio had been suspended for 60 days due to his second violation of the company's Talent Wellness Program policy and that his suspension would expire on June 25.
After eight months, Mysterio returned at a WWE live event on October 17, 2013, and returned to television as part of the Spanish commentary team at Hell in a Cell. On the November 18 episode of Raw, Mysterio saved CM Punk and Daniel Bryan from an attack by The Wyatt Family and The Real Americans (Jack Swagger and Antonio Cesaro), which led to Mysterio being part of a 10-man elimination tag team match at Survivor Series in which Mysterio's team lost after he was eliminated by sole survivor Roman Reigns. At TLC: Tables, Ladders and Chairs Mysterio teamed with Big Show to unsuccessfully challenge Cody Rhodes and Goldust for the WWE Tag Team Championship in a four-way match also involving Rybaxel (Ryback and Curtis Axel) and The Real Americans. At the Royal Rumble pay-per-view on January 26, 2014, Mysterio entered the Royal Rumble match at #30, but was eliminated by Seth Rollins. At WrestleMania XXX, Mysterio competed in the André the Giant Memorial Battle Royal but was eliminated by Cesaro. His last appearance in WWE on the following night on the April 7 episode of Raw, Mysterio lost to a returning Bad News Barrett and subsequently decided to take time off to heal a wrist injury.
On March 20, 2015 Rey Mysterio partnered with Extreme Tiger in a match against the tag team of Aguayo and Manik. Mysterio scored the winning pin on Manik while all involved were unaware that Aguayo was dead (rather than just knocked out) following a regular drop-kick that Mysterio had performed on him during the match. Aguayo was rushed to hospital and doctors attempted to revive him, officially pronouncing him dead at 1:00 AM on March 21, 2015.
During an interview with Title Match Wrestling in December 2016, Mysterio was asked a return to WWE, Mysterio replied:
On April 30, 2017, at the WCPW Pro Wrestling World Cup – Mexican Qualifying Round Mysterio won the Mexico Leg with Penta El Zero M defeating Alberto El Patron in the semi-finals, and defeating long time rival Juventud Guerrera in the finals. In the Round of 16, Mysterio lost to the English qualifier Will Ospreay.
On January 28, 2018, at Royal Rumble, Mysterio was a surprise entrant in the Rumble match as part of a one-time deal with WWE entering at number 27, eliminating Adam Cole before later being eliminated by Finn Bálor.