She auditioned for The Lizzie Bennet Diaries in December 2011, and was selected for the lead role. The Lizzie Bennet Diaries is a web series adapted from Pride and Prejudice. The Lizzie Bennet Diaries won an Emmy Award for the "Best Original Interactive Program". In September 2014, Clements won the Best Actress in a Drama Streamy Award for her role as Lizzie Bennet.
Clements has also starred in The Mortician (2012) and the web series Just Go with It (2015). She has performed in web and TV advertisements, and has narrated audiobooks, among them The Secret Diary of Lizzie Bennet.
In 2016, Clements joined the cast of Edgar Allan Poe's Murder Mystery Dinner Party, where she plays author Charlotte Brontë and also appeared in the romantic comedy film Non-Transferable.
