Brandon Burns was born in Missoula, Montana. He took part in the Missoula Children's Theater until 2002 when his family relocated to Oregon. In 2005, Brandon assisted his brother Cody Burns by taking on the role of lead cameraman for one of his first projects, Guadalajara: The Experience.
However, the studio went on hiatus in 2006 and wouldn't reopen until Brandon's brother and his childhood friend Chris Rex restarted the Prank Calls series in 2009. Brandon was invited by his brother to be a guest star on the first Prank Calls volume, and would from there on forward be one of the main faces of the series' four volume stretch.
Brandon also played an integral role in the Guadalajara: The Experience DVD release in 2010, voicing a new character in an animation segment and giving narration to the lengthy behind the scenes segment.
Brandon has taken part in many Spike Industries projects since, including Second Chances (2011), retro gaming group 3Guys1Wii, and a video game reboot of Spike Industries' Dungeon Warrior (2005).