Zimmer has been married twice. First, to special effects Artist Steve Johnson, whom she met when working on a Duracell TV commercial in the late 1990s.
Zimmer eventually booked her first TV series regular role on the NBC comedy Good Morning, Miami as the lazy and burned-out office assistant, Penny Barrington. After the series was canceled, she spent the second season recurring as Sister Lilly Waters in the CBS drama, Joan of Arcadia, as well as guest-starring in episodes of NYPD Blue and Jake in Progress. Also in 2005, she acted in the short film Just Pray, directed by Tiffani Thiessen. It was accepted into the Tribeca Film Festival.
In early 2006, Zimmer was cast as Brianna, the competitive law undergrad, in the ABC crime/drama series In Justice. She joined the cast of Boston Legal, where she played associate attorney Claire Simms on the show's third season. Her character did not return in season four. Zimmer also portrayed industry powerhouse and studio executive Dana Gordon in the HBO original series Entourage from 2005 to 2011, arguably her most known role to date.
In 2014, she was cast in the series regular role of Quinn King on the Lifetime dramedy series UnREAL. The show has received critical acclaim and Zimmer's performance has garnered high praise.
In 2015, she had a recurring role on season three of ABC's Agents of S.H.I.E.L.D. as Rosalind Price.
Zimmer performed in the world-premiere play, Girls Talk, alongside Brooke Shields, Andrea Bendewald, and Nicole Paggi. The play was written and directed by Roger Kumble. She also starred in the NBC summer series Love Bites as Colleen Rouscher and had a guest appearance on USA’s Royal Pains, playing Psychiatrist Dr. Abby Burton.
