Jack & Jack's comedy career began in 2007 with the creation of their first collaboration YouTube channel MotherFalconQuagmire. The short satires included lip syncing music videos, short parodies of popular songs, and British-speaking lads. Although only made as a side hobby during free time, their videos were received by a considerable audience of hundreds, but faded abruptly not long after the pair started high school.
Prior to their headline tour, Jack & Jack toured alongside artists and social media sensations including Nash Grier, Cameron Dallas, Shawn Mendes and more in 2013.
As part of their partnership with Communications Service Verizon, Jack & Jack have performed at the Verizon Michigan Avenue Destination Store Grand Opening (November 2014) and at the Bayou Music Center to a crowd of 1,500 as part of the Verizon Houston Destination Store Grand Opening (January 2015).
Jack & Jack have previously made appearances at multiple charity events including Miles for Music and at the Camp Ronald McDonald for Good Times fundraiser. They have also shown support to The Fred & Pamela Buffett Cancer Center, in Omaha, Nebraska. They gave a supporting performance at T.J. Martell Foundation's annual New York Family Day event in December 2015.
In January 2018, Jack & Jack were picked as Elvis Duran's Artist of the Month. The duo was featured on NBC's Today show hosted by Hoda Kotb and broadcast nationally where they performed live their single "Beg".