She co-starred in the 1983 episode "Short Notice" during the first season of the Knight Rider television series. In 1991, she portrayed Carol Pulaski on the soap opera General Hospital. In 1993, Curtis portrayed an unrelated Vulcan character disguised as a Romulan (Tallera/T'Paal) in the two-part episode of Star Trek: The Next Generation "Gambit," for which she was screen-tested and not given any special consideration for her previous role as Saavik. In the Babylon 5 episode "Deathwalker" (1994), she appeared as Abbai Ambassador Kalika.
After making frequent appearances in the mid-1990s, as of early 2014 she was only making occasional appearances at Star Trek conventions.
In 2004, Curtis found success as a residential real estate agent in Manlius, New York, in addition to her acting career. In the middle of the following year, she debuted her one-woman show, a work-in-progress, Not My Bra, You Don't! - The Sexual Odyssey of a Forty-Nine Year Old Woman.