He became known as the host of TV's American Idol and KIIS-FM's On Air with Ryan Seacrest.
He had an internship at the radio station WSTR FM and hosted Gladiators 2000 from 1994 to 1996.
He won an Emmy Award for producing Jamie Oliver's Food Revolution and became co-host of Dick Clark's New Year's Rockin' Eve in 2005.
In 2017, he began dating model Shayna Terese Taylor, whom he'd previously dated in 2013 and 2014. He dated Actress Julianne Hough from June 2010 until March 2013. He also dated Hilary Cruz.
He frequently had arguments with Simon Cowell on the set of American Idol.