He trained as an actor from 1981 to 1984 at Studio 34 with Claude Mathieu. In 1984, he was awarded a Diploma of Drama at the Conservatoire national supérieur d'art dramatique in Paris. From 1984 to 1987, he studied with Viviane Theophilides, Michel Bouquet and Jean-Pierre Vincent. At the same time, he entered the Comédie-Française.
He then appeared in numerous television films and gained notoriety with the television series Madame le maire in 1997 and PJ (Police judiciaire). In the latter series, Wolkowitch played Captain/Commander Vincent Fournier. He appeared in the first 100 episodes, from 1997 to March 2006 on France 2. Wolkowitch appeared in flashbacks for several seasons more.
He shares his life with the Actress Fanny Gilles. They met in 2003 on the set of "PJ". They have a daughter, Lou, born in 2006, and a son, born in 2011.
Besides television, he also performs in the theatre. In 2006, he starred in Miss Julie of August Strindberg, with Christine Citti – who played in the first two seasons of PJ – and Émilie Dequenne.
