Lloyd has performed in a variety of live shows since 2006, including The Freewheelin' Cariad Lloyd at Edinburgh Festival Fringe in 2012. In 2013, she performed in The 50 Hour Improvathon at Hoxton Hall, and The Freewheelin' Cariad Lloyd at Soho Theatre among others. In 2014 she performed at the Edinburgh Fringe with Louise Ford in Cariad and Louise's Character Hour.
In 2014 Lloyd starred as Holly in the BBC Three comedy pilot Vodka Diaries and as Poppy in the comedy series Give Out Girls on Comedy Central. In 2015 she played Dawn, a warden in a young offenders' institution in the BBC Three comedy series Crims. She was also a series regular, playing several semi-improvised characters on Murder in Successville with Tom Davis.
In May 2015 she appeared as a panellist on Have I Got News for You and on QI in November 2015 and again in January 2018. She also appeared in the final series of Peep Show in December as Megan. In 2016 Lloyd appeared as a panellist on BBC Radio 4's News Quiz '(Series 17, Episode 1 – April 19)'. In 2018 Lloyd appeared as a panellist on the BBC's Would I Lie to You?.
