She played Larry David's wife on the series Curb Your Enthusiasm.
She worked as a personal assistant to Rob Reiner when she initially moved to Los Angeles to start her career in the entertainment industry.
She was nominated for two Emmy Awards for her work on Curb Your Enthusiasm.
She was previously married to , with whom she had a daughter named Catherine Rose. She then married Robert F. Kennedy Jr. on August 2, 2014.
She starred in the sitcom Suburgatory with Allie Grant.
