After making brief childhood or teenage appearances in films such as Clerks II (2006) and Tusk (2014), she was cast as lead character Colleen McKenzie in the comedy horror films Yoga Hosers (2015) and Moose Jaws (2016).
When she was less than two years old, she made her first big screen appearance in Jay and Silent Bob Strike Back.
She was named for Batman's adversary Harley Quinn.
The daughter of Actress and television personality Jennifer Schwalbach Smith and Director, Producer, and Screenwriter Kevin Smith, she spent her early years in Red Bank, New Jersey.
When she was just four years old, she appeared alongside fellow child actor Paulie Litt in the 2004 feature film Jersey Girl.
