She graduated from St. Ignatius College Preparatory in San Francisco in 2010 and from the University of Michigan in 2014. In addition, she studied at many theatre programs including the Williamstown Theatre Festival as an apprentice, the Movement Theatre Studio in New York, and the Royal Academy of Dramatic Art in London. Her father is of Italian descent. Her mother is of Irish ancestry.
Jacqueline Toboni is known for her guest-starring role of Trubel in the NBC drama Grimm from 2014 to 2017.
In 2015, she appeared on one episode of Major Crimes.
In 2016, she also appeared in four episodes of the Netflix anthology series Easy.
In 2017, she appeared in the sixteenth season of Hell's Kitchen as a guest for episode eleven's dinner Service that honored the contributors from Stand Up to Cancer.
