Servitto appeared as Representative Donald Donatello on the series Brotherhood and had a guest appearance as Carrie Bradshaw's Editor Gabe on Sex and the City. He played Lucky Luciano in the 1992 film Mad Dog Coll. He also voiced the character Sam in the 2002 video game Mafia: The City of Lost Heaven.
He appeared in the 2005 film Hitch as Eddie, he appeared in the episode "Identity" of the series Body of Proof as a father who is mourning the loss of his daughter due to a car crash, and in 2011 he appeared as NYPD Head of Intelligence Deputy Commissioner Soren in "Hall of Mirrors" the 13th episode of the 1st season of the CBS show Blue Bloods.
Since 2012 he has been a series regular on the original HBO series, which plays on Cinemax, Banshee, where he plays Deputy Brock Lotus, and on the Adult Swim television series Your Pretty Face is Going to Hell, where he plays Satan. He also played the role of Dr. Sebastian Reifler for three episodes on the TV series The Blacklist.
