Che started doing stand-up comedy in 2009. He would regularly work several sets per night. In 2012, Che appeared on the Late Show with David Letterman.
He is a winner of New York's Funniest Stand-Up Competition. In 2013, Variety called Che one of "10 Comics to Watch", while Rolling Stone named him one of "The 50 Funniest People."
In 2014, Che appeared in the movie Top Five, appearing as one of Chris Rock's character's friends.
In December 2017, Che was named co-head Writer of Saturday Night Live.
