Initially famous as the winner of the 2002 edition of Australia's Popstars reality talent competition, he went on to release hit singles titled "I'm Moving On" and "Crazy People Rock," as well as albums titled Controlled Folly, Roller Coaster, and Spero.
Prior to his work on Popstars, Cain recorded an album titled Peanut Butter Brick with the Australian band Funkapation.
He hosted the Disney Channel-Australia's AMTV program.
He welcomed his first child, Zoe, when he was only nineteen years old. A decade later, he began raising a son named Max with his fiancee and fellow Popstars contestant, Danielle Stearman.
While on Popstars, Cain performed and recorded an Australian Top 10 cover version of the Stevie Wonder hit "Superstition."