Tucci had a semi-regular role on the television series MDs (2002) and played Amanda Cory on the soap opera Another World from 1993 to 1995. She was a regular cast member on C-16, in the role of Special Agent Anne Rooney, from 1997 to 1998. She played Sergeant Welles in the movie K-911, released direct-to-video in 1999; in 2000, she made an appearance as Dr. Kiera Behrle on CSI: Crime Scene Investigation. She is sometimes credited as 'Christina Tucci'.
