She moved to Mumbai for her internship with documentary Director Siddharth Kak and later started working with advertising agencies like IBW, Bates Clarion and Lowe Lintas, where R. Balki was the creative Director. In following years she made over 100 advertising films and short films; her short film Oh Man! (2001) was selected for the Berlin Film Festival.
She made her feature film debut as a Director with English Vinglish (2012), a film by Shinde's own relationship with her mother, who ran her own pickle Business out of her home in Pune, and was a Marathi-speaking woman, who didn't speak English well, which embarrassed Shinde as a child. As she said in an interview, "I made this film to say sorry to my mother." The film was released on 14 September 2012 at the Toronto International Film Festival followed by its commercial release in India and worldwide on 5 October 2012, and went on to receive both critical and commercial success. Besides the Filmfare Award for Best Debut Director, she was awarded the 'Laadli National Media Awards for Gender Sensitivity'.