Megan Burns was born in Liverpool, England. When Burns was 11 her grandmother sent her to a drama class. From there Burns received a part in the film Liam (2000). She won the Marcello Mastroianni Award at the Venice Film Festival for her performance. Danny Boyle saw this and cast her in his film 28 Days Later, where she played Hannah, one of the survivors of a deadly epidemic.
Her first single release was a double A-side, "Met on the Internet" and "Excuse All the Blood", released 29 May 2006. Her first album Hear Lies was released on 31 October 2006 via iTunes.
The CD version, Here Lies Betty Curse, was released in April 2007. The album's first single, "God This Hurts", was released in August 2007, shortly followed by "Girl with Yellow Hair" on 13 November. In 2006 she performed and won on a Halloween special of the children's television programme The Slammer with "Girl With Yellow Hair".
