Sánchez was born Verónica Sánchez Calderón on July 1, 1977 in Seville, Spain.
Sánchez left her studies of Science in order to study Dramatic Art. From 1996 to 2002, she acted in theater. One of her most successful theater shows was Blood Wedding in 2002.
She became famous as Eva Capdevilla in television series Los Serrano in 2003. At Los Serrano filming set, she met Fran Perea, and they dated for three years. In 2003, she also acted in film Al sur de Granada. For this role, she received ACE, Spanish Actors Union and Goya nominations.
In 2005, Sanchez left Los Serrano. She acted in the film Camarón and received Goya nomination. She also acted in 2005 films El Calentito and Los 2 lados de la cama.
In 2006, she was nominated by Cinema Writers Circle Awards for her role in smash film hit Mia Sarah. She also made the appearance in the 1st episode of television series Génesis: en la mente del asesino.
2007 was very successful for her. She portrayed one of the lead roles in Goya nominated film 13 Roses and Zenitram.