Her first acting part was that of a girl in the drama series Run for Your Life (starring Ben Gazzara) in 1967 when she was 18 years old. Other TV credits include Adam-12, Gunsmoke, The High Chaparral, The Virginian, Medical Center, Walt Disney's Wonderful World of Color, Mod Squad, The F.B.I., Hawaii Five-O, The Love Boat, Fantasy Island, Vega$, B.J. and the Bear, Laverne & Shirley, and State of the Union.
Her voice acting work includes various episodic characters in The Simpsons and the voice of Tina in the 1973 Hanna-Barbera series Goober and the Ghost Chasers.
She portrayed Susan Baker on Adam-12 in the first-season episode "Grand Theft Horse" and Kitty in the episode "The Sand Trap" of the short-lived 1974 ABC police drama Nakia. She played Michael Douglas's girlfriend in The Streets of San Francisco in season two. She had a co-starring role in the short-lived 1977 ABC police series Most Wanted (starring Robert Stack), as well as a small role in the television mini-series Rich Man, Poor Man.
Jo Ann Harris was married to Writer Jerry Belson. They had two children together, Julie and Willi. Jo Ann was widowed when Jerry died in 2006.
