Born in London, Sellers attended Lycée Français de Los Angeles in West Los Angeles and Crossroads School for Arts and Sciences in the class of 1981. She became friends with the "Hollywood Madam" Heidi Fleiss in their teens.
Sellers posed for Playboy in April 1986. In the same year she was indicted for her role in a cocaine-trafficking gang, and was placed on probation for three years.
She performed as a stand-up comic in the early 1990s. With Heidi Fleiss, she hosted and produced an instructional DVD titled Sex Tips with Heidi Fleiss and Victoria Sellers in 2001.
A letter auctioned in 2010, one of the last documents signed by her father before his death, indicates that he was trying to increase the amount of money to be inherited by her from £800 to £20,000.