Owen made her acting debut in the 2009 Peter Jackson film The Lovely Bones, playing Flora Hernandez. From 2010 to 2011, she played the character Puddle Kadubic in the Fox comedy series Running Wilde. Owen co-starred as Dorrit, Carrie Bradshaw's younger rebellious sister, in The CW's The Carrie Diaries, which premiered on January 14, 2013. She had a role in the 2015 comedy slasher film Krampus, directed by Michael Dougherty. She also portrayed Deedee in the drama film Coming Through the Rye. It was announced in August 2017 that Owen was cast in an undisclosed role in the Dick Cheney biopic, titled Backseat, written and directed by Adam McKay.
