Best known for starring as Cleopatra Ofoedo in the TV series Bad Education, Weruche was in 2015 nominated in the "Nollywood Actress of the Year" category at the 2015 Nigeria Entertainment Awards. In 2018, Opia starred alongside Steve Pemberton and Reece Shearsmith in the sixth and final episode of series 4 of Inside No. 9 titled "Tempting Fate". Opia holds a degree in Drama and Sociology.
