McLish was born as Raquel Livia Elizondo in 1955 in Harlingen, Texas, the second-youngest daughter born. Her father Rafael was of Mexican ancestry and her mother is named Raquel Elizondo. She attended the Harlingen High School, where she was a Cheerleader and twice-named Cardinal’s Football Sweetheart. She graduated from high school in 1973. In 1978, she graduated from the University of Texas-Pan American with a degree in physiology and health and nutrition.
McLish is a Christian and describes herself as a compassionate conservative. She has a sister named Sandra Lopez. While attending Pan American University, she met John P. McLish, whom she married on February 3, 1979. They would later divorce. In 1990, she married film Producer Ron Samuels. She and her husband lived in Rancho Mirage, California in 1996. In 2008, she sold her house for $3 million to Boston Red Sox player Coco Crisp.
While attending college, McLish worked at a health club in McAllen, Texas. When she graduated college, she and the manager of the health club she worked at formed a partnership and founded the Sport Palace Association in Harlingen. With the success of the Sport Palace Association, she opened two more facilities in Corpus Christi and Brownsville in 1980. She was inspired to compete in bodybuilding thanks to Lisa Lyon and the men's club manager, Javier Gutierrez, who would show her magazines of female bodybuilders and encouraged her to compete. She decided to compete because the opening of her new health club would coincide with a women's bodybuilding contest and bodybuilding would give her a platform to promote fitness to women.
In a competitive career that spanned only four years, McLish proved a resilient force, never placing lower than third in any contest she entered. In 1981, she lost her Ms. Olympia title to Kike Elomaa, because her physique was not as defined as usual. At the 1982 Ms. Olympia she beat Carla Dunlap to reclaim her title. Both Paulick and Dunlap brought more muscle than McLish in those respective contests, but neither could match McLish's overall appeal. Dunlap defeated her in the 1983 Caesar's World Cup contest. She finished a controversial second behind Cory Everson in the 1984 Ms. Olympia. As quoted by several magazines covering the event, some competitors expressed surprise at McLish's high placement because she didn't carry the muscle mass carried by many of the top women. Though Dunlap, who finished fifth, was the defending Ms. Olympia, the cover of the March 1985 Strength Training for Beauty's March 1985 cover declared "Cory dethrones Rachel."
After finishing second at the 1984 IFBB Ms. Olympia, McLish retired from competitive bodybuilding.
McLish was featured in the 1985 documentary Pumping Iron II: The Women which focused on her participation in the 1983 Caesar’s World Cup. She also acted in the movies Getting Physical (1984), Aces: Iron Eagle III (1992) and Raven Hawk (1996). These involved her acting the part of a physically strong woman. She was one of the first women to take such a role. She was also a star in Herb Alpert's 'Red Hot' music video. She co-starred alongside Arnold Schwarzenegger in the fitness instructional video Shape Up (1982).
McLish has authored two books on weight training for women that made the New York Times bestseller list – Flex Appeal, by Rachel, and Perfect Parts. She is now working on two books that focus on fitness and nutrition.
McLish was the first winner of the Ms. Olympia title. She is one of bodybuilding’s most recognizable personalities. In January 1999, she was inducted into the IFBB Hall of Fame.
