Segal was born and raised in Chester County, Pennsylvania, and has been active in the theatre community in Philadelphia. In 2004 Segal took a break from Temple University to work with area professional theaters.
Over the past few years, Segal has made appearances on Law & Order and in 2006 he appeared in the major motion picture Rocky Balboa. He also acted in such plays as Merlin's Fire, Twelfth Night, Disco Pigs, and According to Goldman.
In Fall 2011, he played the character "U. Gene" on the Fox science-fiction series Fringe. In 2011, he appeared in Body of Proof in episode 3, "Helping Hand". In 2012, he starred in the independent comedy-drama Petunia opposite Thora Birch and Michael Urie. He won a Best Supporting Actor award at the Orlando Film Fest in 2013 for his role in B-Side.
