Later and under the name Antonio de Teffé, he worked behind the scenes in several Italian productions in the early 50's and later acted in several movies, but never really achieving stardom. In 1962, he had a bit part in Sodom and Gomorrah. An early appearance of his was in the 1955 Gli Sbandati.
From 1965 to 1975, the newly named Anthony Steffen achieved considerable fame in Europe, amassing cult status, starring in 27 Spaghetti Westerns. Considered to be an "Italian Clint Eastwood", he was sometimes unfairly criticized for being a stiff or wooden actor. Several of his movies were sizeable box office hits in Europe.
Django the Bastard (aka Stranger's Gundown, 1969) a movie that was produced and written by Steffen, is considered to be an inspiration for Clint Eastwood's High Plains Drifter. In several of his movies, Steffen starred alongside other Spaghetti Western luminaries such as Gianni Garko, Peter Lee Lawrence, and william Berger. Outside of the Spaghetti western genre, Steffen also appeared in several Giallo movies including The Night Evelyn Came Out of the Grave (1971). His roles and status diminished as the Spaghetti Western genre fell into decline. Amassing a considerable fortune from his career as an actor, Steffen embarked on a jet set lifestyle.
Always considered a huge star in Brazil because of the Spaghetti Western popularity in the South American country, Steffen returned to Rio de Janeiro, Brazil in the decade of 1980, until dying of cancer in 2004. He has maintained cult-status among fans of Italian Cinema for being perhaps the most prolific Spaghetti Western Leading actor.